Proton magnetic resonance spectroscopic imaging of the brain in childhood autism.

TitleProton magnetic resonance spectroscopic imaging of the brain in childhood autism.
Publication TypeJournal Article
Year of Publication2003
AuthorsLevitt, JG, O'Neill J, Blanton RE, Smalley S, Fadale D, McCracken JT, Guthrie D, Toga AW, Alger JR
JournalBiological psychiatry
Volume54
Issue12
Pagination1355-66
Date Published2003 Dec 15
ISSN0006-3223
KeywordsAdolescent, Aspartic Acid, Autistic Disorder, Brain, Brain Mapping, Case-Control Studies, Child, Child, Preschool, Choline, Creatine, Female, Humans, Intelligence, Magnetic Resonance Imaging, Male, Spectrometry, X-Ray Emission, Tritium
Abstract

Autism is a developmental disorder of unknown neurologic basis. Based on prior work, we used proton magnetic resonance spectroscopic imaging ((1)H- MRSI) to investigate brain structures, including cingulate and caudate, that we hypothesized would reveal metabolic abnormalities in subjects with autism.

DOI10.1002/hbm.22021
Alternate JournalBiol. Psychiatry