Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia.
|Title||Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia.|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Lencz, T, Bilder RM, Turkel E, Goldman RS, Robinson D, Kane JM, Lieberman JA|
|Journal||Archives of general psychiatry|
|Date Published||2003 Mar|
|Keywords||Adult, Analysis of Variance, Antipsychotic Agents, Attention, Cognition Disorders, Discrimination (Psychology), Female, Humans, Male, memory, Neuropsychological Tests, Pattern Recognition, Visual, Prefrontal Cortex, Reaction Time, Schizophrenia, Schizophrenic Psychology|
Deficits in working memory (WM) have been reported in patients with schizophrenia, but WM is a complex construct dependent on several subprocesses, including input representation (perceptual competency) and holding stimuli on-line (maintenance). A visual delayed match-to-sample task (DMST) was developed to isolate perceptual competency from maintenance during delays. It was hypothesized that patients in the first episode of schizophrenia would exhibit dissociable deficits in both WM domains.
|Alternate Journal||Arch. Gen. Psychiatry|