Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia.

TitleImpairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia.
Publication TypeJournal Article
Year of Publication2003
AuthorsLencz, T, Bilder RM, Turkel E, Goldman RS, Robinson D, Kane JM, Lieberman JA
JournalArchives of general psychiatry
Volume60
Issue3
Pagination238-43
Date Published2003 Mar
ISSN0003-990X
KeywordsAdult, Analysis of Variance, Antipsychotic Agents, Attention, Cognition Disorders, Discrimination (Psychology), Female, Humans, Male, memory, Neuropsychological Tests, Pattern Recognition, Visual, Prefrontal Cortex, Reaction Time, Schizophrenia, Schizophrenic Psychology
Abstract

Deficits in working memory (WM) have been reported in patients with schizophrenia, but WM is a complex construct dependent on several subprocesses, including input representation (perceptual competency) and holding stimuli on-line (maintenance). A visual delayed match-to-sample task (DMST) was developed to isolate perceptual competency from maintenance during delays. It was hypothesized that patients in the first episode of schizophrenia would exhibit dissociable deficits in both WM domains.

Alternate JournalArch. Gen. Psychiatry