Effective components of TORDIA cognitive-behavioral therapy for adolescent depression: preliminary findings.

TitleEffective components of TORDIA cognitive-behavioral therapy for adolescent depression: preliminary findings.
Publication TypeJournal Article
Year of Publication2009
AuthorsKennard, BD, Clarke GN, Weersing RV, Asarnow JR, Shamseddeen W, Porta G, Berk M, Hughes JL, Spirito A, Emslie GJ, Keller MB, Wagner KD, Brent DA
JournalJournal of consulting and clinical psychology
Date Published2009 Dec
KeywordsAdolescent, Affect, Chi-Square Distribution, Child, Cognitive Therapy, Depressive Disorder, Major, Diagnostic and Statistical Manual of Mental Disorders, Emotions, Family, Female, Humans, Male, Odds Ratio, Problem Solving, Serotonin Uptake Inhibitors, Social Behavior, Treatment Outcome

In this report, we conducted a secondary analysis of the Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study to explore the impact of specific cognitive-behavioral therapy (CBT) treatment components on outcome. In TORDIA, 334 youths (ages 12 to 18 years) with major depressive disorder who had failed to respond to an adequate course of selective serotonin reuptake inhibitor (SSRI) medication were randomized to a medication switch (either to an alternative SSRI or venlafaxine) with or without 12 weeks of adjunctive CBT. Participants who had more than 9 CBT sessions were 2.5 times more likely to have adequate treatment response than those who had 9 or fewer sessions. CBT participants who received problem-solving and social skills treatment components, controlling for number of sessions and other confounding variables, were 2.3 and 2.6 times, respectively, more likely to have a positive response. These preliminary findings underscore the importance of receiving an adequate number of sessions to attain an adequate clinical response. Finally, social skills and problem solving may be active elements in CBT for adolescent depression and should be considered in treatment by those working with seriously depressed youths.

Alternate JournalJ Consult Clin Psychol