Cigarette smoking and white matter microstructure.

TitleCigarette smoking and white matter microstructure.
Publication TypeJournal Article
Year of Publication2012
AuthorsHudkins, M, O'Neill J, Tobias MC, Bartzokis G, London ED
JournalPsychopharmacology
Volume221
Issue2
Pagination285-95
Date Published2012 May
ISSN1432-2072
Abstract

Diffusion tensor imaging has been used before in testing associations between cigarette smoking and white matter integrity, with inconsistent results. Published reports indicate higher fractional anisotropy (FA, a measure of linear water diffusion) in some brain regions and lower FA in others in adult smokers compared to nonsmokers. Adolescent smokers exhibited elevated FA at several brain regions and a positive correlation of FA in the genu corpus callosum with exposure to smoking (pack-years).

DOI10.1002/hbm.22021
Alternate JournalPsychopharmacology (Berl.)