Impaired implicit learning in schizophrenia.

TitleImpaired implicit learning in schizophrenia.
Publication TypeJournal Article
Year of Publication2008
AuthorsHoran, WP, Green MF, Knowlton BJ, Wynn JK, Mintz J, Nuechterlein KH
JournalNeuropsychology
Volume22
Issue5
Pagination606-17
Date Published2008 Sep
ISSN0894-4105
KeywordsAdult, Analysis of Variance, cognition, Female, Humans, Learning, Learning Disorders, Male, memory, Middle Aged, Neuropsychological Tests, Probability Learning, Schizophrenia, Task Performance and Analysis, Verbal Learning, Wechsler Scales
Abstract

Schizophrenia patients consistently show deficits on tasks of explicit learning and memory. In contrast, their performance on implicit processing tasks often appears to be relatively intact, although most studies have focused on implicit learning of motor skills. This study evaluated implicit learning in 59 medicated schizophrenia outpatients and 43 controls using 2 different cognitive skill tasks. Participants completed a probabilistic classification task to assess procedural habit learning and an artificial grammar task to assess incidental learning of complex rule-based knowledge, as well as an explicit verbal learning and memory task. In addition to performing worse than controls on the explicit learning task, patients showed worse overall performance on the probabilistic classification task, which involves gradual learning through trial-by-trial performance feedback. However, patients and controls showed similar levels of learning on the artificial grammar task, suggesting a preserved ability to acquire complex rule-based knowledge in the absence of performance feedback. Discussion focuses on possible explanations for schizophrenia patients' poor probabilistic classification task performance.

Alternate JournalNeuropsychology