Altered dynamic coupling of lateral occipital complex during visual perception in schizophrenia.

TitleAltered dynamic coupling of lateral occipital complex during visual perception in schizophrenia.
Publication TypeJournal Article
Year of Publication2011
AuthorsHarvey, P-O, Lee J, Cohen MS, Engel SA, Glahn DC, Nuechterlein KH, Wynn JK, Green MF
JournalNeuroImage
Volume55
Issue3
Pagination1219-26
Date Published2011 Apr 1
ISSN1095-9572
KeywordsAdolescent, Adult, Diagnostic and Statistical Manual of Mental Disorders, Education, Excitatory Postsynaptic Potentials, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neural Pathways, Occipital Lobe, Perceptual Masking, Photic Stimulation, Psychiatric Status Rating Scales, Psychomotor Performance, Schizophrenia, Schizophrenic Psychology, Visual Perception, Young Adult
Abstract

There is mounting evidence that visual perception abnormalities in schizophrenia are partly explained by a dysfunction of the lateral occipital complex (LO). We previously demonstrated that schizophrenia patients had broader topography and reduced magnitude of activity of LO. However, the functional connectivity of LO with other brain regions during visual perception has not been directly investigated in schizophrenia.

DOI10.1111/j.1399-5618.2012.00989.x
Alternate JournalNeuroimage