Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.

TitleAnalysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.
Publication TypeJournal Article
Year of Publication2011
AuthorsGreenwood, TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Freedman R, Braff DL
JournalThe American journal of psychiatry
Volume168
Issue9
Pagination930-46
Date Published2011 Sep
ISSN1535-7228
KeywordsCognition Disorders, Endophenotypes, Epistasis, Genetic, Genetic Association Studies, Genetic Pleiotropy, Genetic Predisposition to Disease, Genotype, Humans, Polymorphism, Single Nucleotide, Schizophrenia
Abstract

The authors used a custom array of 1,536 single-nucleotide polymorphisms (SNPs) to interrogate 94 functionally relevant candidate genes for schizophrenia and identify associations with 12 heritable neurophysiological and neurocognitive endophenotypes in data collected by the Consortium on the Genetics of Schizophrenia.

DOI10.1111/j.1399-5618.2012.00989.x
Alternate JournalAm J Psychiatry