Functional consequences of HIV-associated neuropsychological impairment.

TitleFunctional consequences of HIV-associated neuropsychological impairment.
Publication TypeJournal Article
Year of Publication2009
AuthorsGorman, AA, Foley JM, Ettenhofer ML, Hinkin CH, van Gorp WG
JournalNeuropsychology review
Date Published2009 Jun
KeywordsAcquired Immunodeficiency Syndrome, AIDS Dementia Complex, Anti-Retroviral Agents, Antiretroviral Therapy, Highly Active, Central Nervous System Diseases, Cognition Disorders, Cost of Illness, HIV Infections, Humans, Neuropsychological Tests, Quality of Life

This review focuses on the "real world" implications of infection with HIV/AIDS from a neuropsychological perspective. Relevant literature is reviewed which examines the relationships between HIV-associated neuropsychological impairment and employment, driving, medication adherence, mood, fatigue, and interpersonal functioning. Specifically, the relative contributions of medical, cognitive, psychosocial, and psychiatric issues on whether someone with HIV/AIDS will be able to return to work, adhere to a complicated medication regimen, or safely drive a vehicle will be discussed. Methodological issues that arise in the context of measuring medication adherence or driving capacity are also explored. Finally, the impact of HIV/AIDS on mood state, fatigue, and interpersonal relationships are addressed, with particular emphasis on how these variables interact with cognition and independent functioning. The purpose of this review is to integrate neuropsychological findings with their real world correlates of functional behavior in the HIV/AIDS population.

Alternate JournalNeuropsychol Rev