Mood-state effects on amygdala volume in bipolar disorder.

TitleMood-state effects on amygdala volume in bipolar disorder.
Publication TypeJournal Article
Year of Publication2012
AuthorsFoland-Ross, LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL
JournalJournal of affective disorders
Date Published2012 Aug

Prior structural neuroimaging studies of the amygdala in patients with bipolar disorder have reported higher or lower volumes, or no difference relative to healthy controls. These inconsistent findings may have resulted from combining subjects in different mood states. The prefrontal cortex has recently been reported to have a lower volume in depressed versus euthymic bipolar patients. Here we examined whether similar mood state-dependent volumetric differences are detectable in the amygdala.

Alternate JournalJ Affect Disord