Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease.

TitlePerceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease.
Publication TypeJournal Article
Year of Publication2006
AuthorsErcoli, L, Siddarth P, Huang S-C, Miller K, Bookheimer SY, Wright BC, Phelps ME, Small G
JournalArchives of general psychiatry
Volume63
Issue4
Pagination442-8
Date Published2006 Apr
ISSN0003-990X
KeywordsAged, Aged, 80 and over, Alzheimer Disease, Apolipoprotein E4, Apolipoproteins E, Awareness, Brain, Cognition Disorders, Fluorodeoxyglucose F18, Functional Laterality, Genetic Predisposition to Disease, Genotype, Glucose, Health Status, Heterozygote, Humans, Longitudinal Studies, Memory Disorders, Middle Aged, Neuropsychological Tests, Positron-Emission Tomography, Questionnaires
Abstract

Concerns about age-related memory loss are greater in persons who have the apolipoprotein E-IV (APOE4) genetic risk for Alzheimer disease, but the correlation between the degree of concerns and future cerebral metabolic decline is unknown.

Alternate JournalArch. Gen. Psychiatry