Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.

TitleEarly surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.
Publication TypeJournal Article
Year of Publication2012
AuthorsEngel, J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K
Corporate AuthorsEarly Randomized Surgical Epilepsy Trial(ERSET) Study Group
JournalJAMA : the journal of the American Medical Association
Volume307
Issue9
Pagination922-30
Date Published2012 Mar 7
ISSN1538-3598
KeywordsAdult, Anticonvulsants, cognition, drug resistance, Epilepsy, Temporal Lobe, Female, Humans, Male, Middle Aged, Quality of Life, Seizures, Social Behavior, Temporal Lobe, Time Factors, Treatment Failure, Treatment Outcome
Abstract

Despite reported success, surgery for pharmacoresistant seizures is often seen as a last resort. Patients are typically referred for surgery after 20 years of seizures, often too late to avoid significant disability and premature death.

DOI10.1111/j.1528-1167.2011.03065.x
Alternate JournalJAMA