Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.
|Title||Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.|
|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Engel, J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K|
|Corporate Authors||Early Randomized Surgical Epilepsy Trial(ERSET) Study Group|
|Journal||JAMA : the journal of the American Medical Association|
|Date Published||2012 Mar 7|
|Keywords||Adult, Anticonvulsants, cognition, drug resistance, Epilepsy, Temporal Lobe, Female, Humans, Male, Middle Aged, Quality of Life, Seizures, Social Behavior, Temporal Lobe, Time Factors, Treatment Failure, Treatment Outcome|
Despite reported success, surgery for pharmacoresistant seizures is often seen as a last resort. Patients are typically referred for surgery after 20 years of seizures, often too late to avoid significant disability and premature death.