Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans.
|Title||Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Dean, AC, Sevak RJ, Monterosso JR, Hellemann G, Sugar CA, London ED|
|Journal||Journal of studies on alcohol and drugs|
|Date Published||2011 Nov|
|Keywords||Adult, Amphetamine-Related Disorders, Attention, Benzhydryl Compounds, Case-Control Studies, Cognition Disorders, Cross-Over Studies, Double-Blind Method, Female, Humans, Inhibition (Psychology), Male, Memory, Short-Term, Methamphetamine, Middle Aged, Neuroprotective Agents, Young Adult|
Individuals who are methamphetamine dependent exhibit higher rates of cognitive dysfunction than healthy people who do not use methamphetamine, and this dysfunction may have a negative effect on the success of behavioral treatments for the disorder. Therefore, a medication that improves cognition, such as modafinil (Provigil), may serve as a useful adjunct to behavioral treatments for methamphetamine dependence. Although cognitive-enhancing effects of modafinil have been reported in several populations, little is known about the effects of modafinil in methamphetamine-dependent individuals. We thus sought to evaluate the effects of modafinil on the cognitive performance of methamphetamine-dependent and healthy individuals.
|Alternate Journal||J Stud Alcohol Drugs|