Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder.

TitleDemographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder.
Publication TypeJournal Article
Year of Publication2008
AuthorsCullen, B, Samuels JF, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Greenberg BD, Knowles JA, Piacentini J, Bienvenu JO, Grados MA, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang K-Y, Hoehn-Saric R, Nestadt G
JournalDepression and anxiety
Volume25
Issue3
Pagination218-24
Date Published2008
ISSN1091-4269
KeywordsAdult, Age Factors, Age of Onset, Attitude to Health, Comorbidity, Diagnostic and Statistical Manual of Mental Disorders, Female, Health Status, Humans, Logistic Models, Male, mood disorders, Obsessive-Compulsive Disorder, Patient Acceptance of Health Care, Personality Inventory, Psychiatric Status Rating Scales, Sex Factors, Time Factors
Abstract

This study investigated the demographic and clinical factors that influence treatment status in family members with obsessive compulsive disorder (OCD). Six hundred and two subjects from the OCD Collaborative Genetics Study were interviewed using the Structured Clinical Interview for DSM-IV (SCID) to diagnose Axis I disorders, and the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) for assessment of OCD symptoms. The demographic and clinical data were compared between subjects who had received treatment and those who had not. A precipitous onset of symptoms, severe illness, multiple obsessions and compulsions, and co-morbid affective disorders were all positively associated with receiving treatment. Older age and the presence of obsessive compulsive personality disorder (OCPD) or OCPD traits were negatively associated with treatment. Gender and age at onset of symptoms did not predict treatment history. The mean duration from onset of symptoms to receiving treatment was 13.8+/-SD 11.9 years, but there was a direct relationship between current age and time to treatment, with younger subjects receiving treatment sooner. Clinical factors are predominant in predicting treatment status in family members with OCD. Although the mean duration from onset of symptoms to treatment was long, younger family members appear to receive treatment sooner.

DOI10.1016/j.brat.2011.06.001
Alternate JournalDepress Anxiety