Longitudinal study of herpes simplex virus type 2 infection using viral dynamic modelling.

TitleLongitudinal study of herpes simplex virus type 2 infection using viral dynamic modelling.
Publication TypeJournal Article
Year of Publication2007
AuthorsCrespi, CM, Cumberland WG, Wald A, Corey L, Blower S
JournalSexually transmitted infections
Volume83
Issue5
Pagination359-64
Date Published2007 Aug
ISSN1368-4973
KeywordsAdult, Cervix Uteri, Cohort Studies, Female, Herpes Genitalis, Herpesvirus 2, Human, Humans, Longitudinal Studies, Middle Aged, Models, Biological, Recurrence, Vagina, Vaginal Smears, Virus Activation, Virus Shedding
Abstract

Rates of reactivation of herpes simplex virus type 2 (HSV-2) change over time and these changes affect transmission and clinical management strategies. We conducted a longitudinal study of HSV-2 infection to quantify rates of change in HSV-2 reactivation, mucosal shedding and recurrences of genital lesions, using a newly available model of HSV within-host dynamics.

Alternate JournalSex Transm Infect