Is aversive learning a marker of risk for anxiety disorders in children?
|Title||Is aversive learning a marker of risk for anxiety disorders in children?|
|Publication Type||Journal Article|
|Year of Publication||2008|
|Authors||Craske, MG, Waters AM, Lindsey Bergman R, Naliboff B, Lipp OV, Negoro H, Ornitz EM|
|Journal||Behaviour research and therapy|
|Date Published||2008 Aug|
|Keywords||Anxiety Disorders, Avoidance Learning, Case-Control Studies, Child, Cues, Diagnostic and Statistical Manual of Mental Disorders, Discrimination (Psychology), Extinction, Psychological, Female, Galvanic Skin Response, Humans, Male, Risk Factors|
Aversive conditioning and extinction were evaluated in children with anxiety disorders (n=23), at-risk for anxiety disorders (n=15), and controls (n=11). Participants underwent 16 trials of discriminative conditioning of two geometric figures, with (CS+) or without (CS-) an aversive tone (US), followed by 8 extinction trials (4 CS+, 4 CS-), and 8 extinction re-test trials averaging 2 weeks later. Skin conductance responses and verbal ratings of valence and arousal to the CS+/CS- stimuli were measured. Anxiety disordered children showed larger anticipatory and unconditional skin conductance responses across conditioning, and larger orienting and anticipatory skin conductance responses across extinction and extinction re-test, all to the CS+ and CS-, relative to controls. At-risk children showed larger unconditional responses during conditioning, larger orienting responses during the first block of extinction, and larger anticipatory responses during extinction re-test, all to the CS+ and CS-, relative to controls. Also, anxiety disordered children rated the CS+ as more unpleasant than the other groups. Elevated skin conductance responses to signals of threat (CS+) and signals of safety (CS-; CS+ during extinction) are discussed as features of manifestation of and risk for anxiety in children, compared to the specificity of valence judgments to the manifestation of anxiety.
|Alternate Journal||Behav Res Ther|