Considerations in the selection and conditioning of Old World monkeys for laboratory research: animals from domestic sources.

TitleConsiderations in the selection and conditioning of Old World monkeys for laboratory research: animals from domestic sources.
Publication TypeJournal Article
Year of Publication2006
AuthorsCapitanio, JP, Kyes RC, Fairbanks LA
JournalILAR journal / National Research Council, Institute of Laboratory Animal Resources
Volume47
Issue4
Pagination294-306
Date Published2006
ISSN1084-2020
KeywordsAcclimatization, Animal Welfare, Animals, Animals, Domestic, Animals, Laboratory, Cercopithecidae, Conditioning (Psychology), Diet, Housing, Animal, Laboratory Animal Science, Photoperiod, Socialization, Time Factors, Transportation
Abstract

Nonhuman primates from domestic sources constitute an important resource for the research community. The life history of the Old World monkey species that comprise the bulk of this resource is described, and issues that colony managers and researchers alike should consider regarding animal selection (e.g., species, age, sex, rearing history, temperament, genotype, viral status, geographic origin) are discussed. Preparation of domestically bred animals for research usually involves some combination of social separation, relocation, resocialization, alterations in physical space, photoperiod, and diet, as well as exposure to novel environments. The research literature that has focused on these issues is reviewed, and authors suggest that once animals have been assigned to their project housing situation, a period ranging up to 3 mo (depending on the magnitude of the change in housing) might be warranted before an experimental protocol should begin. Attention to issues of animal selection and conditioning by both researchers and colony managers can lead to the shared goal of high-quality research that utilizes the minimal number of animals.

DOI10.1002/hipo.20954
Alternate JournalILAR J