Structural and functional neuroimaging in Alzheimer's disease: an update.

TitleStructural and functional neuroimaging in Alzheimer's disease: an update.
Publication TypeJournal Article
Year of Publication2002
AuthorsBurggren, AC, Bookheimer SY
JournalCurrent topics in medicinal chemistry
Volume2
Issue4
Pagination385-93
Date Published2002 Apr
ISSN1568-0266
KeywordsAlzheimer Disease, Brain, Humans, Magnetic Resonance Imaging, Tomography, Emission-Computed
Abstract

The field of neuroimaging has made several recent advances understanding Alzheimer's disease, a debilitating disease which affects approximately 4 million people in the United States [1]. Despite recent therapeutic advances, available treatments at present are aimed primarily at slowing progression of the disease rather than halting it completely or reversing its progression. Early detection of the disease has, therefore, been a major focus of a variety of neuroimaging techniques, including Positron Emission Tomography (PET), functional Magnetic Resonance Imaging (fMRI), and structural MRI. Recently, these techniques have also been found to be useful in monitoring cognitive and pathological progression of the disease, as well as monitoring response to clinical intervention treatment. A methodology review will be included here as well as a critical evaluation of the advantages and disadvantages of the various techniques.

Alternate JournalCurr Top Med Chem