Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression.
|Title||Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Brooks, JO, Foland-Ross LC, Thompson PM, Altshuler LL|
|Date Published||2011 Jul 30|
|Keywords||Adult, Bipolar disorder, Brain, Brain Mapping, Female, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Male, Middle Aged, Psychiatric Status Rating Scales|
A preliminary within-subjects MRI study of seven patients with a diagnosis of bipolar I disorder revealed that, compared to remission, depression was associated with gray matter density increases in subgenual prefrontal cortex, parahippocampal gyrus, and inferior temporal gyri. Decreases were observed in superior and inferior frontal gyri and anterior cingulate.
|Alternate Journal||Psychiatry Res|