A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort.
|Title||A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort.|
|Publication Type||Journal Article|
|Year of Publication||2010|
|Authors||Binder, EB, Jeffrey Newport D, Zach EB, Smith AK, Deveau TC, Altshuler LL, Cohen LS, Stowe ZN, Cubells JF|
|Journal||Journal of psychiatric research|
|Date Published||2010 Jul|
|Keywords||Adult, Cohort Studies, Depression, Postpartum, Depressive Disorder, Major, Female, Genetic Predisposition to Disease, Humans, Odds Ratio, Polymorphism, Genetic, Predictive Value of Tests, Pregnancy, Risk Factors, Serotonin Plasma Membrane Transport Proteins, Severity of Illness Index|
Peripartum major depressive disorder (MDD) is a prevalent psychiatric disorder with potential detrimental consequences for both mother and child. Despite its enormous health care relevance, data regarding genetic predictors of peripartum depression are sparse. The aim of this study was to investigate associations of the serotonin-transporter linked polymorphic region (5-HTTLPR) genotype with peripartum MDD in an at-risk population.
|Alternate Journal||J Psychiatr Res|