Are antidepressants associated with new-onset suicidality in bipolar disorder? A prospective study of participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

TitleAre antidepressants associated with new-onset suicidality in bipolar disorder? A prospective study of participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Publication TypeJournal Article
Year of Publication2006
AuthorsBauer, MS, Wisniewski SR, Marangell LB, Chessick CA, Allen MH, Dennehy EB, Miklowitz DJ, Thase ME, Sachs GS
JournalThe Journal of clinical psychiatry
Volume67
Issue1
Pagination48-55
Date Published2006 Jan
ISSN0160-6689
KeywordsAdult, Antidepressive Agents, Bipolar disorder, Cohort Studies, Depressive Disorder, Major, Female, Follow-Up Studies, Humans, Male, Outcome Assessment (Health Care), Prospective Studies, Risk Assessment, Suicide, Suicide, Attempted
Abstract

Depressive episodes are common in bipolar disorder, and the disorder is characterized by high suicide rates. Recent analyses indicate a possible association of antidepressant treatment and suicidality in children and adults with depressive or anxiety disorders. However, few data are available to inform the suicidality risk assessment of antidepressant use specifically in bipolar disorder.

DOI10.1038/npp.2011.192
Alternate JournalJ Clin Psychiatry