The association of DRD4 and novelty seeking is found in a nonhuman primate model.
|Title||The association of DRD4 and novelty seeking is found in a nonhuman primate model.|
|Publication Type||Journal Article|
|Year of Publication||2007|
|Authors||Bailey, JN, Breidenthal SE, Jorgensen MJ, McCracken JT, Fairbanks LA|
|Date Published||2007 Feb|
|Keywords||Analysis of Variance, Animals, Cercopithecus aethiops, DNA, Exploratory Behavior, Genetic Variation, Models, Animal, Phenotype, Polymorphism, Genetic, Receptors, Dopamine D4, Social Behavior|
The association of novelty seeking with a repeat polymorphism in the coding region of the dopamine D4 receptor gene (DRD4) has been demonstrated in several human populations, but not in others. The objective of this study was to test the generality of the association in a captive nonhuman primate population of known history, using objective methods for assessing novelty seeking and a pedigree-based association design.
|Alternate Journal||Psychiatr. Genet.|