The UCLA longitudinal study of neurocognitive outcomes following mild pediatric traumatic brain injury.

TitleThe UCLA longitudinal study of neurocognitive outcomes following mild pediatric traumatic brain injury.
Publication TypeJournal Article
Year of Publication2011
AuthorsBabikian, T, Satz P, Zaucha K, Light R, Lewis RS, Asarnow RF
JournalJournal of the International Neuropsychological Society : JINS
Volume17
Issue5
Pagination886-95
Date Published2011 Sep
ISSN1469-7661
KeywordsAdolescent, Attention, Brain Injuries, California, Child, Cognition Disorders, Disease Progression, Female, Humans, Language, Longitudinal Studies, Male, memory, Neuropsychological Tests, Psychomotor Performance, Severity of Illness Index, Time Factors, Universities
Abstract

Comprehensive reviews of neurocognitive outcomes following mild, uncomplicated traumatic brain injury (TBI) in children have shown minimal effects on neurocognition, especially in methodologically rigorous studies. In this study, we report longitudinal (1, 6, and 12 months post injury) results in four domains of neurocognitive functioning in a large sample of children with mild TBI (n = 124, ages 8-17 at injury) relative to two demographically matched control groups (other injury: n = 94 and non-injury: n = 106). After accounting for age and parental education, significant main effects of group were observed on 7 of the 10 neurocognitive tests. However, these differences were not unique to the TBI sample but were found between both the TBI and other injury groups relative to the non-injured group, suggesting a general injury effect. Effects were primarily within the domains measuring memory, psychomotor processing speed, and language. This is the largest longitudinal study to date of neurocognitive outcomes at discrete time points in pediatric mild TBI. When controlling for pre-injury factors, there is no evidence of long-term neurocognitive impairment in this group relative to another injury control group. The importance of longitudinal analyses and use of appropriate control groups are discussed in the context of evaluating the effects of mild TBI on cognition.

DOI10.3791/1786
Alternate JournalJ Int Neuropsychol Soc