Left hemisphere motor facilitation in response to manual action sounds.

TitleLeft hemisphere motor facilitation in response to manual action sounds.
Publication TypeJournal Article
Year of Publication2004
AuthorsAziz-Zadeh, L, Iacoboni M, Zaidel E, Wilson S, Mazziotta J
JournalThe European journal of neuroscience
Volume19
Issue9
Pagination2609-12
Date Published2004 May
ISSN0953-816X
KeywordsAdolescent, Adult, Auditory Perception, Electric Stimulation, Evoked Potentials, Motor, Female, Functional Laterality, Hand, Humans, Magnetics, Male, Middle Aged, Motor Cortex, Movement, Muscle, Skeletal, Physical Stimulation, Psychomotor Performance, Pyramidal Tracts, Sound
Abstract

Previous studies indicate that the motor areas of both hemispheres are active when observing actions. Here we explored how the motor areas of each hemisphere respond to the sounds associated with actions. We used transcranial magnetic stimulation (TMS) to measure motor corticospinal excitability of hand muscles while listening to sounds. Sounds associated with bimanual actions produced greater motor corticospinal excitability than sounds associated with leg movements or control sounds. This facilitation was exclusively lateralized to the left hemisphere, the dominant hemisphere for language. These results are consistent with the hypothesis that action coding may be a precursor of language.

DOI10.1002/gps.3790
Alternate JournalEur. J. Neurosci.