Neurocognitive impairments in nonpsychotic parents of children with schizophrenia and attention-deficit/hyperactivity disorder: the University of California, Los Angeles Family Study.

TitleNeurocognitive impairments in nonpsychotic parents of children with schizophrenia and attention-deficit/hyperactivity disorder: the University of California, Los Angeles Family Study.
Publication TypeJournal Article
Year of Publication2002
AuthorsAsarnow, RF, Nuechterlein KH, Subotnik KL, Fogelson DL, Torquato RD, Payne DL, Asamen J, Mintz J, Guthrie D
JournalArchives of general psychiatry
Volume59
Issue11
Pagination1053-60
Date Published2002 Nov
ISSN0003-990X
KeywordsAdolescent, Adult, Attention Deficit Disorder with Hyperactivity, Brain Damage, Chronic, Case-Control Studies, Child, Child of Impaired Parents, Cognition Disorders, Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Psychometrics, Risk, Schizophrenia, Childhood
Abstract

We tested the hypotheses that certain neurocognitive impairments index genetic liability to schizophrenia and that childhood-onset schizophrenia (COS) is a variant of adult-onset schizophrenia (AOS) by determining whether parents of COS probands show the types of neurocognitive impairments found in relatives of AOS probands.

DOI10.1111/j.1469-8986.2012.01383.x
Alternate JournalArch. Gen. Psychiatry