Amygdala astrocyte reduction in subjects with major depressive disorder but not bipolar disorder.

TitleAmygdala astrocyte reduction in subjects with major depressive disorder but not bipolar disorder.
Publication TypeJournal Article
Year of Publication2010
AuthorsAltshuler, LL, Abulseoud OA, Foland-Ross L, Bartzokis G, Chang S, Mintz J, Hellemann G, Vinters HV
JournalBipolar disorders
Volume12
Issue5
Pagination541-9
Date Published2010 Aug
ISSN1399-5618
KeywordsAdult, Amygdala, Astrocytes, Bipolar disorder, Cell Count, Depressive Disorder, Major, Female, Glial Fibrillary Acidic Protein, Humans, Male, Middle Aged, Schizophrenia
Abstract

Several magnetic resonance imaging studies have found changes in amygdala volumes in adults with mood disorders. The cellular basis for these changes has not been explored in detail. Specifically, it is not known whether differences in the density and/or volume of neurons or glial cells contribute to tissue volume changes seen on magnetic resonance images.

DOI10.1111/j.1399-5618.2012.01008.x
Alternate JournalBipolar Disord