Acceleration and augmentation strategies for treating bipolar depression.
|Title||Acceleration and augmentation strategies for treating bipolar depression.|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Altshuler, LL, Frye MA, Gitlin MJ|
|Date Published||2003 Apr 15|
|Keywords||Adrenergic beta-Antagonists, Antidepressive Agents, Antimanic Agents, Antipsychotic Agents, Bipolar disorder, Combined Modality Therapy, Depressive Disorder, Humans, Lithium, Pindolol, Randomized Controlled Trials as Topic, sleep deprivation, Thyroid Hormones|
Despite the prevalence and morbidity of bipolar depression, few randomized treatment trials have been conducted to assess clinical efficacy. Even fewer studies have assessed approaches that optimize treatment response for bipolar depression. This review will define three types of common combination strategies--adjunctive, acceleration and augmentation--and discuss the limited literature of controlled studies reported on acceleration and augmentation approaches.
|Alternate Journal||Biol. Psychiatry|