James Waschek

Waschek James A Noggin on heaven's door: a factor that promotes the selective production of serotonergic neurons from murine embryonic stem cells and induced pluripotent stem cells.. Journal of neurochemistry. 2012; 122(1): 1-3.

Ji Haofeng, Zhang Yu, Shen Xiuda, Gao Feng, Huang Cynthia Y, Abad Catalina, Busuttil Ronald W, Waschek James A, Kupiec-Weglinski Jerzy W Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation via cAMP-PKA pathway.. Hepatology (Baltimore, Md.). 2012; 166(1): .

Abad Catalina, Tan Yossan-Var, Cheung-Lau Gardenia, Nobuta Hiroko, Waschek James A VIP deficient mice exhibit resistance to lipopolysaccharide induced endotoxemia with an intrinsic defect in proinflammatory cellular responses.. PloS one. 2012; 7(5): e36922.

Tan Yossan-Var, Waschek James A Targeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis.. ASN neuro. 2011; 3(4): .

Hirose Megumi, Niewiadomski Pawel, Tse Gary, Chi Gloria C, Dong Hongmei, Lee Alice, Carpenter Ellen M, Waschek James A Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures.. Journal of neuroscience research. 2011; 89(9): 1363-74.

Loh Dawn H, Dragich Joanna M, Kudo Takashi, Schroeder Analyne M, Nakamura Takahiro J, Waschek James A, Block Gene D, Colwell Christopher S Effects of vasoactive intestinal Peptide genotype on circadian gene expression in the suprachiasmatic nucleus and peripheral organs.. Journal of biological rhythms. 2011; 26(3): 200-9.

Abad Catalina, Waschek James A Immunomodulatory roles of VIP and PACAP in models of multiple sclerosis.. Current pharmaceutical design. 2011; 17(10): 1025-35.

Ghiani Cristina A, Mattan Natalia S, Nobuta Hiroko, Malvar Jemily S, Boles Julie, Ross Michael G, Waschek James A, Carpenter Ellen M, Fisher Robin S, de Vellis Jean Early effects of lipopolysaccharide-induced inflammation on foetal brain development in rat.. ASN neuro. 2011; 3(4): .

Abad Catalina, Tan Yossan-Var, Lopez Robert, Nobuta Hiroko, Dong Hongmei, Phan Phu, Feng Ji-Ming, Campagnoni Anthony T, Waschek James A Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis.. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(45): 19555-60.

Dragich Joanna M, Loh Dawn H, Wang Louisa M, Vosko Andrew M, Kudo Takashi, Nakamura Takahiro J, Odom Irene H, Tateyama Sei, Hagopian Arkady, Waschek James A, Colwell Christopher S The role of the neuropeptides PACAP and VIP in the photic regulation of gene expression in the suprachiasmatic nucleus.. The European journal of neuroscience. 2010; 31(5): 864-75.

Cohen Joseph R, Resnick Daniel Z, Niewiadomski Pawel, Dong Hongmei, Liau Linda M, Waschek James A Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.. BMC cancer. 2010; 10(1): 676.

Kim Woo-Kyun, Meliton Vicente, Park Kye Won, Hong Cynthia, Tontonoz Peter, Niewiadomski Pawel, Waschek James A, Tetradis Sotirios, Parhami Farhad Negative regulation of Hedgehog signaling by liver X receptors.. Molecular endocrinology (Baltimore, Md.). 2009; 23(10): 1532-43.

Tan Yossan-Var, Abad Catalina, Lopez Robert, Dong Hongmei, Liu Shen, Lee Alice, Gomariz Rosa P, Leceta Javier, Waschek James A Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis.. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(6): 2012-7.

Girard Beatrice M, Malley Susan E, Braas Karen M, Waschek James A, May Victor, Vizzard Margaret A Exaggerated Expression of Inflammatory Mediators in Vasoactive Intestinal Polypeptide Knockout (VIP(-/-)) Mice with Cyclophosphamide (CYP)-Induced Cystitis.. Journal of molecular neuroscience : MN. 2008; 36(1-3): 188-99.

Niewiadomski Pawel, Coûté-Monvoisin Anne-Claire, Abad Catalina, Ngo Danny, Menezes Adrian, Waschek James A Mice Deficient in both Pituitary Adenylyl Cyclase-activating Polypeptide and Vasoactive Intestinal Peptide Survive, but Display Growth Retardation and Sex-dependent Early Death.. Journal of molecular neuroscience : MN. 2008; 36(1-3): 200-7.

Lim Maria A, Stack Conor M, Cuasay Katrina, Stone Madeleine M, McFarlane Hewlet G, Waschek James A, Hill Joanna M Regardless of genotype, offspring of VIP-deficient female mice exhibit developmental delays and deficits in social behavior.. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2008; 26(5): 423-34.

Stack Conor M, Lim Maria A, Cuasay Katrina, Stone Madeleine M, Seibert Kimberly M, Spivak-Pohis Irit, Crawley Jacqueline N, Waschek James A, Hill Joanna M Deficits in social behavior and reversal learning are more prevalent in male offspring of VIP deficient female mice.. Experimental neurology. 2008; 211(1): 67-84.

Nemetz Nicole, Abad Catalina, Lawson Greg, Nobuta Hiroko, Chhith Seririthanar, Duong Lucy, Tse Gary, Braun Jonathan, Waschek James A Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP.. International journal of cancer. Journal international du cancer. 2008; 122(8): 1803-9.

Lelievre Vincent, Seksenyan Akop, Nobuta Hiroko, Yong William H, Chhith Seririthanar, Niewiadomski Pawel, Cohen Joseph R, Dong Hongmei, Flores Avegail, Liau Linda M, Kornblum Harley I, Scott Matthew P, Waschek James A Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.. Developmental biology. 2008; 313(1): 359-70.

Armstrong B D, Abad C, Chhith S, Cheung-Lau G, Hajji O E, Nobuta H, Waschek J A Impaired nerve regeneration and enhanced neuroinflammatory response in mice lacking pituitary adenylyl cyclase activating peptide.. Neuroscience. 2008; 151(1): 63-73.

Nakano Ichiro, Masterman-Smith Michael, Saigusa Kuniyasu, Paucar Andres A, Horvath Steve, Shoemaker Lorelei, Watanabe Momoko, Negro Alejandra, Bajpai Ruchi, Howes Amy, Lelievre Vincent, Waschek James A, Lazareff Jorge A, Freije William A, Liau Linda M, Gilbertson Richard J, Cloughesy Timothy F, Geschwind Daniel H, Nelson Stanley F, Mischel Paul S, Terskikh Alexey V, Kornblum Harley I Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.. Journal of neuroscience research. 2008; 86(1): 48-60.

Loh Dawn H, Abad Catalina, Colwell Christopher S, Waschek James A Vasoactive intestinal peptide is critical for circadian regulation of glucocorticoids.. Neuroendocrinology. 2008; 88(4): 246-55.

Lelievre V, Favrais G, Abad C, Adle-Biassette H, Lu Y, Germano P M, Cheung-Lau G, Pisegna J R, Gressens P, Lawson G, Waschek J A Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's disease.. Peptides. 2007; 28(9): 1688-99.

Koh Shay-Whey M, Guo Yan, Bernstein Steve L, Waschek James A, Liu Xiuhuai, Symes Aviva J Vasoactive intestinal peptide induction by ciliary neurotrophic factor in donor human corneal endothelium in situ.. Neuroscience letters. 2007; 423(2): 89-94.

Lacombe Arnaud, Lelievre Vincent, Roselli Charles E, Muller Jean-Marc, Waschek James A, Vilain Eric Lack of vasoactive intestinal peptide reduces testosterone levels and reproductive aging in mouse testis.. The Journal of endocrinology. 2007; 194(1): 153-60.

Said Sami I, Hamidi Sayyed A, Dickman Kathleen G, Szema Anthony M, Lyubsky Sergey, Lin Richard Z, Jiang Ya-Ping, Chen John J, Waschek James A, Kort Smadar Moderate pulmonary arterial hypertension in male mice lacking the vasoactive intestinal peptide gene.. Circulation. 2007; 115(10): 1260-8.

Lelievre Vincent, Ghiani Cristina A, Seksenyan Akop, Gressens Pierre, de Vellis Jean, Waschek James A Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation.. Regulatory peptides. 2006; 137(1-2): 58-66.

Szema Anthony M, Hamidi Sayyed A, Lyubsky Sergey, Dickman Kathleen G, Mathew Suni, Abdel-Razek Tarek, Chen John J, Waschek James A, Said Sami I Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP.. American journal of physiology. Lung cellular and molecular physiology. 2006; 291(5): L880-6.

Abad Catalina, Gomariz Rosa P, Waschek James A Neuropeptide mimetics and antagonists in the treatment of inflammatory disease: focus on VIP and PACAP.. Current topics in medicinal chemistry. 2006; 6(2): 151-63.

Girard Beatrice A, Lelievre Vincent, Braas Karen M, Razinia Tannaz, Vizzard Margaret A, Ioffe Yevgeniya, El Meskini Rajaa, Ronnett Gabriele V, Waschek James A, May Victor Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice.. Journal of neurochemistry. 2006; 99(2): 499-513.

Waschek James A, Dicicco-Bloom Emanuel, Nicot Arnaud, Lelievre Vincent Hedgehog signaling: new targets for GPCRs coupled to cAMP and protein kinase A.. Annals of the New York Academy of Sciences. 2006; 1070(10): 120-8.

Galbraith Gary, Waschek James, Armstrong Brian, Edmond John, Lopez Ivan, Liu Weixin, Kurtz Ira Murine auditory brainstem evoked response: putative two-channel differentiation of peripheral and central neural pathways.. Journal of neuroscience methods. 2006; 153(2): 214-20.

Lacombe Arnaud, Lelievre Vincent, Roselli Charles E, Salameh Wael, Lue Yan-he, Lawson Gregory, Muller Jean-Marc, Waschek James A, Vilain Eric Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice.. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(10): 3793-8.

Armstrong Brian D, Abad Catalina, Chhith Seririthanar, Cheung-Lau Gardenia, Hajji Omar E, Coute Anne-Claire, Ngo Danny H, Waschek James A Impairment of axotomy-induced pituitary adenylyl cyclase-activating peptide gene expression in T helper 2 lymphocyte-deficient mice.. Neuroreport. 2006; 17(3): 309-12.

Aton Sara J, Colwell Christopher S, Harmar Anthony J, Waschek James, Herzog Erik D Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons.. Nature neuroscience. 2005; 8(4): 476-83.

Armstrong Brian D, Abad Catalina, Chhith Seririthanar, Rodriguez Williams, Cheung-Lau Gardenia, Trinh Van, Waschek James A Restoration of axotomy-induced PACAP gene induction in SCID mice with CD4+ T-lymphocytes.. Neuroreport. 2004; 15(17): 2647-50.

Itri Jason, Michel Stephan, Waschek James A, Colwell Christopher S Circadian rhythm in inhibitory synaptic transmission in the mouse suprachiasmatic nucleus.. Journal of neurophysiology. 2004; 92(1): 311-9.

Colwell Christopher S, Michel Stephan, Itri Jason, Rodriguez Williams, Tam J, Lelievre Vincent, Hu Zhou, Liu X, Waschek James A Disrupted circadian rhythms in VIP- and PHI-deficient mice.. American journal of physiology. Regulatory, integrative and comparative physiology. 2003; 285(5): R939-49.

Armstrong Brian D, Hu Zhongting, Abad Catalina, Yamamoto Miya, Rodriguez Williams I, Cheng Jennifer, Tam Jimmy, Gomariz Rosa P, Patterson Paul H, Waschek James A Lymphocyte regulation of neuropeptide gene expression after neuronal injury.. Journal of neuroscience research. 2003; 74(2): 240-7.

Hu Zhongting, Lelievre Vincent, Rodriguez Williams I, Cheng Jennifer W, Waschek James A Comparative distributions of pituitary adenylyl cyclase-activating polypeptide and its selective type I receptor mRNA in the frog (Xenopus laevis) brain.. Regulatory peptides. 2002; 109(1-3): 15-26.

Nicot Arnaud, Lelièvre Vincent, Tam Jimmy, Waschek James A, DiCicco-Bloom Emanuel Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002; 22(21): 9244-54.

Waschek James A Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration.. Developmental neuroscience. 2002; 24(1): 14-23.

Lelievre Vincent, Hu Zhongting, Byun Ji-Yun, Ioffe Yevgeniya, Waschek James A Fibroblast growth factor-2 converts PACAP growth action on embryonic hindbrain precursors from stimulation to inhibition.. Journal of neuroscience research. 2002; 67(5): 566-73.