|Title||A web-based brain atlas of the vervet monkey, Chlorocebus aethiops.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Woods, RP , Fears SC , Jorgensen MJ , Fairbanks LA , Toga AW , Freimer NB |
|Date Published||2011 Feb 1|
|Keywords||Animals , Atlases as Topic , Brain , Brain Mapping , Cercopithecus aethiops , Computer Graphics , Data Interpretation, Statistical , Image Processing, Computer-Assisted , Informatics , Internet , Macaca mulatta , Magnetic Resonance Imaging , Species Specificity , Stereotaxic Techniques |
Vervet monkeys are a frequently studied animal model in neuroscience research. Although equally distantly related to humans, the ancestors of vervets diverged from those of macaques and baboons more than 11 million years ago, antedating the divergence of the ancestors of humans, chimpanzees and gorillas. To facilitate anatomic localization in the vervet brain, two linked on-line electronic atlases are described, one based on registered MRI scans from hundreds of vervets (http://www.loni.ucla.edu/Research/Atlases/Data/vervet/vervetmratlas/verv... ) and the other based on a high-resolution cryomacrotome study of a single vervet (http://www.loni.ucla.edu/Research/Atlases/Data/vervet/vervetatlas/vervet... ). The averaged MRI atlas is also available as a volume in Neuroimaging Informatics Technology Initiative format. In the cryomacrotome atlas, various sulcal and subcortical structures have been anatomically labeled and surface rendered views are provided along the primary planes of section. Both atlases simultaneously provide views in all three primary planes of section, rapid navigation by clicking on the displayed images, and stereotaxic coordinates in the averaged MRI atlas space. Despite the extended time period since their divergence, the major sulcal and subcortical landmarks in vervets are highly conserved relative to those described in macaques.