If humans are genetically related to chimps, why did our brains develop the innate ability for language and speech while theirs did not?
Scientists suspect that part of the answer to the mystery lies in a gene called FOXP2. When mutated, FOXP2 can disrupt speech and language in humans. Now, a UCLA–Emory University study reveals major differences between how the human and chimp versions of FOXP2 work, perhaps explaining why language is unique to humans. Published Nov. 11 in the online edition of the journal Nature, the findings provide insight into the evolution of the human brain and may point to possible drug targets for human disorders characterized by speech disruption, such as autism and schizophrenia.
This program provides specialized avalutation and treatment for individuals with Schizophrenia and related disorders or sysptoms, such as psychotic behavior, auditory or visual hallucinations, incoherence, delusional, and paranoia. Visit the Section on Psychosis website for useful reference information.
Disruptions also found in cellular pathways involved in memory and cognition
Schizophrenia is a devastating mental disease, thought to be caused by the interaction of both genetic and environmental factors. Because there is no biochemical test that can identify the disorder, physicians rely upon the recognition of its symptoms — which can include auditory hallucinations and paranoia — in order to make their diagnosis.
White matter 'integrity' may be predictive of functional outcome
The goal of the Section on Psychosis is to improve the lives of people with psychotic illnesses (including schizophrenia and schizoaffective disorder) through a multi-disciplinary program that includes research, education, and clinical care. We are convinced that the care of individuals with these illnesses should be guided by the best evidence from research. Since psychotic illnesses are caused by disordered functioning of the brain, we also believe that research focused on the brain will lead to better treatments.
Clinical research programs in the Section on Psychosis are available for a broad range of individuals including patients who are at high risk for schizophrenia or schizoaffective disorder and those with early signs, patients recently diagnosed with these illnesses, and patients who have lived with these illnesses for years.
Schizophrenia is a severe psychiatric disease characterized by disorganized behavior, delusions and hallucinations. Sadly, there is no clear understanding of its cause. Now, in a collaborative study, UCLA and Dutch researchers have identified three new candidate genes for schizophrenia that may contribute to a better understanding of how the disease evolves.
UCLA Scientist Awarded $3.8 Million Grant for International Study to Identify Genetic Links to Schizophrenia
The National Institute of Mental Health has awarded Roel A. Ophoff, Ph.D., assistant professor of human genetics at the David Geffen School of Medicine at UCLA, a $3.8 million grant to lead a four-year genetic study of schizophrenia in collaboration with scientists from the University Medical Center (UMC) Utrecht in the Netherlands.