No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front and sides of the brain, the disease can lead to dramatic changes in a patient's personality and behavior, including the loss of the ability to communicate. Now, UCLA scientists have discovered that a key signaling pathway plays an important role in the brain disorder and may offer a potential target for treatment. The journal Neuron publishes the findings in its Sept. 22 edition.
MSNBC.com reported July 18 about research linking head injuries and dementia among U.S. military personnel and professional football players. The story cited brain-imaging research conducted by Dr. Gary Small, Parlow-Solomon Professor on Aging, a professor of psychiatry at the Semel Institute and director of the UCLA Longevity Center. Small was quoted.
Brain, Behavior, and Aging Research Center
We are a research group investigating Alzheimer's disease (AD) and other dementias. We use neuroimaging procedures, such as PET and MRI, to understand how the brain is changed in dementia. We also test memory and other thinking skills, and interview our patients to understand what types of emotional problems they are having (such as depression or irritability). We combine all of this information to help us understand the symptoms of dementia and the brain changes that contribute to the illness.
Our lab is also involved in treatment studies. In these experiments, we prescribe medication(s), and then test patients to understand how the drug is helping. We are conducting clinical trials both for FDA approved medications and for a new investigational drug to treat AD.
Friends of Semel Event Open Mind Lecture 'Growing Up with Undiagnosed Asperger's'
Tim Page was diagnosed with Asperger's syndrome 3 years after being awarded the Pulitzer prize for music criticism. Parallel Play tells the story of a child with an unexplained ability to memorize vast parts of the encyclopedia but not pass basic math and science classes. His book, written with newfound clarity, is a story of success not in spite of the syndrome, but because of it.
Refreshments and book signing.
Parking $9 in Lot 7. www.ucla.edu/maps
Admission free but reservations are required. Please call 310-825-8871 or email email@example.com
Friends of Semel Event Open Mind Lecture 'Sanity and Grace, a Journal of Suicide, Surviaval and Strength
Renowned singer/songwriter Judy Collins's deeply moving memoir chronicles her journey from pain to survival following the suicide of her son, and offers comfort to those who struggle in suicide's aftermath.
Friends of Semel Event Open Mind Lecture 'Against Medical Advice' by James Patterson and Hal Friedman