Global elimination of trachoma: how frequently should we administer mass chemotherapy?

TitleGlobal elimination of trachoma: how frequently should we administer mass chemotherapy?
Publication TypeJournal Article
Year of Publication1999
AuthorsLietman, T, Porco T, Dawson C, Blower S
JournalNature medicine
Volume5
Issue5
Pagination572-6
Date Published1999 May
ISSN1078-8956
KeywordsTrachoma
Abstract

The World Health Organization has recommended repeat mass drug administration as part of their global initiative to eliminate blinding trachoma by the year 2020. The efficacy of repeat treatment will be tested empirically, but the results will not be available for many years, and recommendations for the necessary frequency of treatment are needed immediately. We have developed a mathematical model that uses available epidemiological data from a variety of countries. We recommend, based on our analysis, that in areas where trachoma is moderately prevalent (<35% in children), it should be treated annually, but hyperendemic areas (>50% in children), it should be treated biannually.

URLhttp://www.semel.ucla.edu/sites/all/files/biomedicalmodeling/pdf/trachoma.pdf
Alternate JournalNat Med

Semel Institute at UCLAJane & Terry Semel Institute for Neuroscience & Human Behavior

760 Westwood Plaza

Los Angeles, CA 90095