Today’s Standard Treatment Was Yesterday’s Clinical Trial

Research studies help us advance our knowledge of autism spectrum disorders, leading to earlier diagnosis and better treatments. These discoveries are possible due to the generous contributions from families participating in research studies. Your child may be eligible to participate in one of UCLA CART’s many research studies. We invite you to partner in this discovery process with us.

* All studies are free and medical insurance is not required.

Age range Study
Infants under 6-weeks Identifying Early Signs of Autism in High-risk Infants
0 months - 2 years Neurodevelopmental Studies in Infants with Tuberous Sclerosis Complex TSC
12 - 21 months Intervention Study for Young Children Showing Early Signs of Autism
33 - 39 months Identifying Children With Autism Spectrum Disorders And Developmental Delays
5 - 14 years Treatment with Guanfacine for Hyperactive Children with Autism
6 - 11 years Treatment with Aripiprazole and Behavior Intervention for Children with Autism who have Low Language Ability
6 - 13 years Treatment with Therapy for Study for Children with Autism
7 - 14 years Physiology of Anxiety in Children with Autism
7 - 17 years Brain Imaging in Children with Autism
8 - 16 years Treatment with Risperidone for Repetitive Behaviors in Children with Autism
11 - 18 years Social Skills Training for Children/Teens with Autism

Identifying Early Signs of Autism in High-risk Infants

Eligibility

  • Infants under the age of 6-weeks (pregnant women are encouraged to contact us)
  • Have two siblings with autism or one sibling and a close relative with an ASD.

Purpose

  • To discover the earliest signs of autism in infants at high-risk of developing autism and identify children who may benefit from early intervention.

Involvement

This study involves several visits to UCLA during your baby’s first year and will include:

  • EEG
  • MRI
  • Eye tracking
  • Developmental assessments
  • Blood draws

Benefits

Children showing early signs of autism may be eligible to participate in an early intervention study.

Contact

Brigid McCarthy at bmccarthy@mednet.ucla.edu or (310) 825-3478

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Neurodevelopmental Studies in Infants with Tuberous Sclerosis Complex TSC

Eligibility

Children 0 months-3 years of age diagnosed with Tuberous Sclerosis Complex (TSC)

Purpose

Identify early signs of autism in children with TSC

Involvement

  • EEG
  • Behavioral measurements
  • Neurological exam
  • Up to 7 visits to UCLA over 3 years

Benefits

Frequent and early behavioral and developmental screenings

Contact

Tina Shimizu at cshimizu@mednet.ucla.edu or (310) 825-0180

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Intervention Study for Young Children Showing Early Signs of Autism

Eligibility

  • Children 12 – 21 months of age
  • Delays in smiling, crawling and speaking

Purpose

To improve social and communication skills in children who have early signs of autism.

Involvement

  • Free-based parent training at UCLA (weekly for 8-weeks)
  • Developmental assessments

Benefits

Your child may improve his/her social and communication skills

Contact

kasarilab@mednet.ucla.edu or (310) 206-1268

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Identifying Children With Autism Spectrum Disorders And Development Delays

Eligibility

  • Children 33-39 months of age
  • With developmental delays NOT suspected to be an Autism Spectrum Disorder OR
  • Delays consistent with an ASD (language delay, social impairment, or repetitive behaviors

Purpose

To more quickly and accurately identify children with developmental delays or an ASD

Involvement

  • Two visits at UCLA, less than 3 hours total
  • Observations of child's behavior and questionnaires for the parent about their child
  • Developmental Assessments

Benefits

  • Participants will receive $50
  • Free developmental assessments

Contact

Joni Zuckerbrow-Miller at jzuckerbrow@mednet.ucla.edu or (310) 794 2215

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Treatment with Guanfacine for Hyperactive Children with Autism

Eligibility

  • Children 5-14 years of age with an ASD
  • Hyperactive/impulsive behaviors

Purpose

To help reduce hyperactive/impulsive behaviors in children with autism

Involvement

  • Participants will receive guanfacine or placebo (some children may also receive methylphenidate)
  • Questionnaires, interviews, psychological testing
  • Laboratory testing

Benefits

Your child may have a decrease in hyperactive/impulsive behaviors

Contact

Jenny Cowen at jcowen@mednet.ucla.edu or (310) 825-6170

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Treatment with Aripiprazole and Behavior Intervention for Children with Autism who have Low Language Ability

Eligibility

  • Children 6-11 years of age with an ASD
  • Low language abilitiy

Purpose

To examine the combined effects of medication and a behavioral intervention on language development in children with autism.

Involvement

  • Participants will receive aripiprazole or placebo
  • Questionnaires, interviews, psychological testing
  • Laboratory testing

Benefits

Children may have an increase in language ability

Contact

Jenny Cowen at jcowen@mednet.ucla.edu or (310) 825-6170

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Treatment with Therapy for Study for Children with Autism

Eligibility

Children 6-13 years of age diagnosed with an ASD

Purpose

To help improve social skills with peers

Involvement

  • 32 weeks (48 hrs) of free therapy
  • Psychological testing, interviews, questionnaires
  • School Observations

Benefits

  • Free of charge therapy for 32 weeks (48 hours)
  • Improved social skills

Contact

Mithi Del Rosario at mdelrosario@mednet.ucla.edu or (310) 206-2586

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Physiology of Anxiety in Children with Autism

Eligibility

Children 7-14 years of age with an ASD

Purpose

To better understand the physiology related to emotions and anxiety in youth with an ASD

Involvement

  • 1-2 visits to UCLA
  • Questionnaires, interviews, psychological testing
  • Saliva collection (small sample)

Benefits

  • Participants will receive $100
  • Free of charge diagnostic evaluation (abilities, cognitive functioning and adaptive skills)

Contact

Lindsey Sterling at lsterling@mednet.ucla.edu or (310) 267-5272

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Treatment with Risperidone for Repetitive Behaviors in Children with Autism

Eligibility

  • Children 8-16 years of age with an ASD
  • Repetitive behaviors or narrow interests

Purpose

To help reduce repetitive behaviors in children with autism

Involvement

  • Participants will receive risperidone or placebo
  • Questionnaires, interviews, psychological testing
  • Laboratory testing
  • MRI

Benefits

Children may have a decrease in repetitive behaviors

Contact

Jenny Cowen at jcowen@mednet.ucla.edu or (310) 825-6170

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Brain Imaging Study for Children with Autism

Eligibility

Children 7-17 years of age diagnosed with an ASD

Purpose

To learn more about genetic and brain differences between girls and boys

Involvement

  • MRI
  • Psychological testing, interviews, questionnaires
  • Blood test
  • EEG

Benefits

  • Participants will receive up to $100
  • Picture of your child’s brain

Contact

Devi Beck-Pancer at dbeckpancer@mednet.ucla.edu or (310) 206-4482

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Social Skills Training in Children/Teens with Autism

Eligibility

Children 11-18 years of age with an ASD

Purpose

To improve social skills

Involvement

Weekly social skills groups for 14-weeks (parent must also participate)

Benefits

  • May improve social skills
  • After the study is completed, participants may keep device (iTouch) containing Virtual Coach mobile application
  • Free of charge diagnostic evaluation (abilities, cognitive functioning and adaptive skills)

Contact

Liz Laugeson at peersclinic@ucla.edu or (310) 267-3377

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